Shot Based Analysis
AVMA Principles of Vaccination
One a Day
What the Experts Say
AVMA Has Studied Vaccination Issues
Approved by the American Veterinary Medical Association
Executive Board, April 2001, published in the Journal of the
American Veterinary Medical Association, Volume 219, No. 5,
September 1, 2001.
Medical decisions about vaccine selection and protocols have
become more complex. Selecting vaccine products and recommending
vaccine programs are among the most complicated of medical decisions
facing veterinarians. The reasons are numerous: continued evolution
of our understanding of the immune system; increased value of
animals to the owner/client; improved medical-record systems,
and longer life-spans allowing the emergence of chronic sequele.
Improved understanding of infectious diseases, the strengths
and limitations of the biologic regulatory-approval process,
and adverse events associated with vaccination also complicate
decisions required for best patient care.
The Council on Biologic and Therapeutic Agents (COBTA) has studied
the issues of vaccinology and immunology for the past two years.
This study included a review of the scientific literature and
interactive testimony with four expert groups including academic,
regulatory, industry, and practitioner experts. Topics included
safety, efficacy, duration of immunity, research and development
of vaccines, vaccine licensing, product labeling, adverse events
and adverse event reporting, governmental oversight of manufacturers,
and legal issues associated with medical procedures.
Vaccines have played a significant role in enabling people and
animals to live longer in this world filled with microbial pathogens.
Vaccine products vary in efficacy and safety. Modern science
continues to learn more about the immune systems and to develop
strategies and technology for safer and more efficacious vaccines.
Thorough evaluations of the risks of the disease, and those
potentially associated with the vaccine, compared to the benefits
for the patient, are necessary in crafting optimal health recommendations
that include vaccination.